甲基-β-環糊精, SIGMA C4555-10G
分類 其他生化試劑
級別 優級純GR
產品規格 SIGMA C4555-10G
CAS 128446-36-6
品牌 SIGMA
用途范圍 生物科研
保存溫度 常溫
中文名稱 甲基-β-環糊精
英文名稱 Methyl-β-cyclodextrin
供應商 上海研伴實業有限公司
甲基-β-環糊精 SIGMA C4555-10G
powder, BioReagent, suitable for cell culture
· 產品編號：C4555
· 中文名稱：甲基-β-環糊精
· 英文名稱：Methyl-β-cyclodextrin
· CAS號：128446-36-6
· 保存溫度：常溫
訂貨信息：
產品規格價格(RMB)
· C4555-1G 電儀/元
· C4555-5G 電儀/元
· C4555-10G 電儀/元
注：此價格僅供參考，請以SIGMA價格為準，優惠價請電詢。
性能描述
Application
用于提高細胞培養應用中非極性物質如脂肪酸、脂類、維生素以及*的溶解度。
Reconstitution
室溫下攪拌 30 分鐘可得到溶液。或者，采用超聲處理并冷卻。溶液可在 4°C 下存放數月。固體應在室溫下密封儲存。
General description
Cyclodextrins are cyclic oligosaccharides consisting of 6, 7, or 8 glucopyranose units, usually referred to as α-, β-, or γ-cyclodextrins, respectively. These compounds have rigid doughnut-shaped structures making them natural complexing agents. The unique structures of these compounds owe their stability to intramolecular hydrogen bonding between the C2- and C3-hydroxyl groups of neighboring glucopyranose units. The molecule takes on the shape of a torus with the C2- and C3-hydroxyls located around the larger opening and the more reactive C6-hydroxyl aligned around the smaller opening. The arrangement of C6-hydroxyls opposite the hydrogen bonded C2- and C3-hydroxyls forces the oxygen bonds into close proximity within the cavity, leading to an electron rich, hydrophobic interior. The size of this hydrophobic cavity is a function of the number of glucopyranose units forming the cyclodextrin.
The solubility of natural cyclodextrins is very poor. In the late 1960’s, it was discovered that chemical substitutions at the 2, 3, and 6 hydroxyl sites would greatly increase solubility. Most chemically modified cyclodextrins are able to achieve a 50% (w/v) concentration in water.
Cavity size is the major determinant as to which cyclodextrin is used in complexation. The cavity diameter of β-cyclodextrins or β-glucopyranose unit compounds is well-suited for use with molecules the size of hormones, vitamins and many compounds frequently used in tissue and cell culture applications. For this reason, β-cyclodextrin is most commonly used as a complexing agent.
性質
Related Categories | Cell Biology Cell Culture Cell Signaling and Neuroscience Chelation/Complexation Compounds Chemical Synthesis更多... |
product line | BioReagent |
form | powder |
extent of labeling | 1.5-2.1 methyl per mol glucose |
mp | 180-182 °C(lit.) |
solubility | H2O: soluble50 mg/mL |
suitability | suitable for cell culture |
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