Anti-LYVE-1抗體,品牌淋巴管內(nèi)皮透明質(zhì)酸受體抗體抗體應(yīng)用于WB、IHC、IF、ELISA等實驗中，產(chǎn)品貨期快、質(zhì)量品牌保障，并提供完善的售前、售中、售后服務(wù)！咨詢或在線客服！我們將竭誠為您服務(wù)！公司堅持對產(chǎn)品質(zhì)量作不斷的評估、創(chuàng)新和改善以確保您對我們產(chǎn)品的高度信任！
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英文名稱 LYVE-1
抗體名稱 Anti-LYVE-1抗體,品牌淋巴管內(nèi)皮透明質(zhì)酸受體抗體
別    名 LYVE1; lymphalic vessel endotheilial hyaluronan receptor 1; CRSBP 1; CRSBP1; extracellular link domain containing 1; extracellular link domain-containing 1; HAR; hyaluronic acid receptor; Cell surface retention sequence-binding protein 1; CRSBP-1; extracellular link domain-containing 1; Extracellular link domain-containing protein 1; Lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1_HUMAN; Lymphatic endothelium specific hyaluronan receptor; LYVE 1; LYVE-1; XLKD1.   
研究領(lǐng)域 心血管  細胞生物  免疫學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human LYVE-1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

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產(chǎn)品介紹 The lymphatic vasculature forms a second circulatory system that drains extracellular fluid from the tissues and provides an exclusive environment in which immune cells can encounter and respond to foreign antigen. Recently a number of interesting molecules have been identified that may be exploited as markers for lymphatic endothelium, including the hyaluronan receptor LYVE1, PALE, VEGFR3, podoplanin. LYVE1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is compley absent from blood vessels. Hence, LYVE1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves. 
淋巴管內(nèi)皮透明質(zhì)酸受體抗體儲存溫度：存在于血清、組織培養(yǎng)上清液或腹水中的抗體在-20℃下能夠*儲存。低溫存放不會損傷抗體活性。抗體的工作液通常儲存于4℃中。此溫度下，抗體的活性能穩(wěn)定數(shù)月至數(shù)年亦不損失。抗體溶液不應(yīng)反復(fù)凍融，因為反復(fù)凍融將導(dǎo)致部分抗體失活并產(chǎn)生不需要的蛋白—蛋白凝聚物。抗體的凝聚能導(dǎo)致活性喪失。這是由于抗原結(jié)合位點的空間構(gòu)象被破壞，或由于產(chǎn)生的不溶物被離心或過濾而除去。冷凝蛋白類的抗體不能存放于4℃。因為在4℃下此類抗體會發(fā)生沉淀。一些鼠源性IgG3亞類的抗體有此特性。如果抗體在4℃下發(fā)生沉淀，就應(yīng)該存放于室溫下的疊氮鈉溶液中。
保存條件：低溫
運輸：4度，或干冰。
公司抗體具有高純度、高效價、高特異性的特點，僅用于科學(xué)研究，不可用于臨床診斷及藥物治療，可以應(yīng)用于多種實驗。