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技術文章

β淀粉樣肽(31-35)抗體說明書

閱讀:777發布時間:2012-9-25

博研生物為您推薦: β淀粉樣肽(31-35)抗體

Rabbit Anti-beta-Amyloid(31-35)

Catalog Number :BYK-
0871R       
Quantity size :   0.1ml (dilute with pH 7.4    0.01 M PBS or antibody diluent )
 
Background:  The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid antibodies and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.
 
Specificity :   
        Anti- beta-Amyloid(31-35) is a rabbit polyclonal antibody unconjugated                
        specific for beta-Amyloid(31-35) of hu, mo, rat, cow, dog, pig, hrs, Rb, chk, Gpig          
         use for western blotting,elisa,immunoprecipitation and immunohistochemistry
         Protein G affinity chromatography purification, purity :>95%
         Isotype:  IgG
         mol wt:  4.4kDa
 
Application :  
        Western blotting 1:100-500                
         Immunohistochemistry 1:100-500                 
         ELISA 1:500-1000                  
         Optimal working dilutions must be determined by the end user.
 
Storage: Store at -20 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4
 
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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