Anti-Socs 1抗體說(shuō)明書(shū),現(xiàn)貨供應(yīng)
Catalog Number : RS-0113R
Quantity size : 0.1ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ）
Anti-Socs 1抗體說(shuō)明書(shū)操作Background:
Interacts with multiple activated signaling proteins of the tyrosine kinase signaling pathway including JAK family kinases, TEC, KIT, GRB2 and VAV. Binding to JAKs is mediated through the KIR and SH2 domains to a phosphorylated tyrosine residue within the JAK JH1 domain. Binds the SH3 domain of GRB2 via diproline determinants in the N-terminus, and the N-terminal regulatory domain of VAV （By similarity）. Interacts with the Elongin BC complex （TCEB1 and TCEB2）. Component of an ECS CBC（SOCS1） E3 ubiquitin-protein ligase complex which contains Elongin BC, CUL5, RBX1 and SOCS1 （By similarity）. Interacts （via SH2 domain and SOCS box） with TRIM8 （By similarity）. Interacts with AXL, CUL2 and FGFR3. Interacts with INSR （By similarity）
pecificity :
– Anti-Socs 1s a rabbit monoclonal antibody unconjugated
– specific foAnti-Socs 1 of human, mouse, rat，cow
– use for western blotting,elisa,immunoprecipitation and immunohistochemistry
– Protein G affinity chromatography purification, purity :>95%
– Isotype: IgG
– mol wt: 12.5 kDa
Anti-Socs 1抗體說(shuō)明書(shū)操作Application :
– Western blotting 1:100-500
– Immunohistochemistry 1:100-500
– ELISA 1:500-1000
– Optimal working dilutions must be determined by the end user.
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Anti-Socs 1抗體說(shuō)明書(shū)操作
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