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Anti-Mouse F4/80 Antigen PE 抗小鼠F4/80抗原PE抗體

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產品型號eBiosience12-4801-82

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更新時間:2023-07-24 19:04:44瀏覽次數:3035次

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Host
Rat
Isotype
IgG2a, kappa
Reactivity
Mouse
Conjugate
PE
Laser
Blue Laser, Green Laser, Yellow-Green Laser
Emit
575 nm
Excite
488 - 561 nm
Reported Applications
Flow Cytometric Analysis

Also known as: Pan Macrophage Marker

Clone: BM8

Description: The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximay 125 kDa transmembrane protein. The F4/80 antigen is expressed by a majority of mature macrophages and is the best marker for this population of cells. However, other cell types such as Langerhans cells and liver Kupffer cells have been reported to express this antigen. Expression of F4/80 commences during early myeloid development and is upregulated on all BM cells stimulated in vitro with M-CSF. It has been shown that some cytokines downregulate the expression of F4/80 resulting in lack of F4/80 antigen on a subpopulation of macrophages, especially in the lymphoid microenvironment in vivo

Host Rat
Isotype IgG2a, kappa
Reactivity Mouse
Conjugate PE
Laser Blue Laser, Green Laser, Yellow-Green Laser
Emit 575 nm
Excite 488 - 561 nm
Reported Applications Flow Cytometric Analysis

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