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珀金埃爾默醫學診斷產品（上海）有限公司
珀金埃爾默醫學診斷產品（上海）有限公司
Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazin......
Frozen Cells validated for calcium testing: Serotonin 5-HT3A channel, human recombinant, in HEK293 host cell. We provide one vial of frozen cells (10 million cells/vial). Some of our Frozen cells may be restricted for sale in specified countries. Please inquire at your local sales office for more information. You are authorized to utilize these frozen cell preparations one time only. Any attempt to transfer, re-use, or propagate these cells is expressly unauthorized and a violation of the product terms and conditions of sale.
Features:
The AequoScreen technology is a generic GPCR technology which can be used with Gs, Gi and Gq coupled GPCRs and calcium coupled ion channels. Following receptor stimulation, increases in intracellular calcium enable measurement of the resulting flash luminescence signal.
The frozen cells approach to functional testing consists in the dissociation of cell culture from testing. That means that we will culture the cells and freeze them with an optimized protocol to stop all replication. These cells are then stored in liquid nitrogen or simply in a -80°C freezer, thawed and used directly in a functional, cellular GPCR test with previously validated performance.
| 檢測目標類 | Ion channel |
|---|---|
| 檢測目標類型 | Cell line |
| 檢測驗證 | Calcium Luminescence |
| 宿主細胞 | HEK293 |
| 產品品牌名稱 | AequoZen |
| 包裝量 | 18.0 Million Cells |
| 受體類型 | 5-Hydroxytryptamine (Serotonin) |
| 第二信使釋放 | Calcium flux |
| 運輸條件 | 干冰 |
| 治療領域 | Central Nervous System |
| 產品尺寸 | 1 vial |
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