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Chemokine CCR8 receptor (human recombinant) AequoZen Frozen Cells

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Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazin......

詳細(xì)介紹

AequoZen^® Double Transfected Cell Lines: CCR8 receptor, human recombinant, in CHO-K1 host cell. One vial of non-propagatable cells is shipped per order. A detailed technical dossier includes sequence, culture conditions and pharmacological properties of the recombinant receptor. All cell lines are tested for the absence of mycoplasma. Terms and conditions apply. Some products are not available in some countries. Please inquire at your local sales office for more information.

Features:

Ready-to-use cells; no cell culture required (dispense and assay)
Fully automatable and miniaturizable to 1536
Enables reduction in reagents and consumable costs
High signal to background ratio enabling detection of agonists, antagonists and allosteric modulators
Robust assay (Z', CV values, solvent resistance)
Reduces the number of false positives from autofluorescent compounds in screening libraries
Option to work with cells in suspension to increase throughput
Amenable for use with calcium coupled ion channels and tyrosine kinase receptors

AequoZen technology is a generic GPCR technology which can be used with Gs, Gi and Gq coupled GPCRs and calcium coupled ion channels. Following receptor stimulation, increases in intracellular calcium enable measurement of the resulting flash luminescence signal.

規(guī)格

檢測(cè)目標(biāo)類	GPCR
檢測(cè)驗(yàn)證	Calcium Luminescence
自動(dòng)化兼容	Yes
宿主細(xì)胞	CHO-K1
產(chǎn)品品牌名稱	AequoZen
受體類型	Chemokine
運(yùn)輸條件	干冰
治療領(lǐng)域	Inflammation
產(chǎn)品尺寸	10 million cells