RanBP7抗體,說明書RAN結(jié)合蛋白7/Importin 7抗體抗體應(yīng)用于WB、IHC、IF、ELISA等實(shí)驗(yàn)中,產(chǎn)品貨期快、質(zhì)量品牌保障,并提供完善的售前、售中、售后服務(wù)!咨詢或在線客服!我們將竭誠為您服務(wù)!公司堅(jiān)持對(duì)產(chǎn)品質(zhì)量作不斷的評(píng)估、創(chuàng)新和改善以確保您對(duì)我們產(chǎn)品的高度信任!
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RanBP7抗體,說明書RAN結(jié)合蛋白7/Importin 7抗體產(chǎn)品介紹 Importin 7 is a 1,038 amino acid protein encoded by the human gene IPO7. Importin-7 belongs to the importin b family and contains one importin N-terminal domain. Importin-7 functions in nuclear protein import, either by acting as an autonomous nuclear transport receptor or as an adapter-like protein in association with the Importin b subunit KPNB1. Acting autonomously, Importin-7 is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to Importin-7, the Importin-7/substrate complex dissociates and Importin-7 is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. Importin-7 is a nuclear protein that is expressed in most tissues.
RAN結(jié)合蛋白7/Importin 7抗體儲(chǔ)存溫度:存在于血清、組織培養(yǎng)上清液或腹水中的抗體在-20℃下能夠*儲(chǔ)存。低溫存放不會(huì)損傷抗體活性。抗體的工作液通常儲(chǔ)存于4℃中。此溫度下,抗體的活性能穩(wěn)定數(shù)月至數(shù)年亦不損失。抗體溶液不應(yīng)反復(fù)凍融,因?yàn)榉磸?fù)凍融將導(dǎo)致部分抗體失活并產(chǎn)生不需要的蛋白—蛋白凝聚物。抗體的凝聚能導(dǎo)致活性喪失。這是由于抗原結(jié)合位點(diǎn)的空間構(gòu)象被破壞,或由于產(chǎn)生的不溶物被離心或過濾而除去。冷凝蛋白類的抗體不能存放于4℃。因?yàn)樵?℃下此類抗體會(huì)發(fā)生沉淀。一些鼠源性IgG3亞類的抗體有此特性。如果抗體在4℃下發(fā)生沉淀,就應(yīng)該存放于室溫下的疊氮鈉溶液中。
保存條件:低溫
運(yùn)輸:4度,或干冰。
公司抗體具有高純度、高效價(jià)、高特異性的特點(diǎn),僅用于科學(xué)研究,不可用于臨床診斷及藥物治療,可以應(yīng)用于多種實(shí)驗(yàn)。
英文名稱 RanBP7
抗體名稱
別 名 Imp 7; Imp7; Importin-7; Importin7; IPO 7; IPO7; IPO7_HUMAN; Ran binding protein 7; Ran-binding protein 7; RANBP 7; RanBP7.
研究領(lǐng)域 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 119kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human RanBP7/Importin 7
亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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