HAS3抗體,說明書透明質酸合成酶3抗體抗體應用于WB、IHC、IF、ELISA等實驗中,產品貨期快、質量品牌保障,并提供完善的售前、售中、售后服務!咨詢或在線客服!我們將竭誠為您服務!公司堅持對產品質量作不斷的評估、創新和改善以確保您對我們產品的高度信任!
訂購:或(成)客服
HAS3抗體,說明書透明質酸合成酶3抗體產品介紹 HAS1, HAS2 and HAS3 are HA (hyaluronan or hyaluronic acid) synthase proteins. The extracellular matrix in most vertebrates express HA, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by b-1,3 and b-1,4 glycosidic bonds. The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix. Both HAS1 and HAS2 synthesize high molecular-weight HA, whereas HAS3 produces lower molecular weight HA. The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli, suggesting distinct functional roles of the three proteins. HAS3 produces both secreted and cell-associated forms of hyaluronan and is the most active of the three isoforms of this enzyme in adults. HAS3 gene expression plays a crucial role in the regulation of hyaluronan synthesis in the epidermis. Specifically, IFN-g markedly upregulates HAS3 mRNA, whereas TGF Beta downregulates HAS3 transcript levels. The human HAS3 gene maps to chromosome 16q22.1.
透明質酸合成酶3抗體儲存溫度:存在于血清、組織培養上清液或腹水中的抗體在-20℃下能夠*儲存。低溫存放不會損傷抗體活性。抗體的工作液通常儲存于4℃中。此溫度下,抗體的活性能穩定數月至數年亦不損失。抗體溶液不應反復凍融,因為反復凍融將導致部分抗體失活并產生不需要的蛋白—蛋白凝聚物。抗體的凝聚能導致活性喪失。這是由于抗原結合位點的空間構象被破壞,或由于產生的不溶物被離心或過濾而除去。冷凝蛋白類的抗體不能存放于4℃。因為在4℃下此類抗體會發生沉淀。一些鼠源性IgG3亞類的抗體有此特性。如果抗體在4℃下發生沉淀,就應該存放于室溫下的疊氮鈉溶液中。
保存條件:低溫
運輸:4度,或干冰。
公司抗體具有高純度、高效價、高特異性的特點,僅用于科學研究,不可用于臨床診斷及藥物治療,可以應用于多種實驗。
英文名稱 HAS3
抗體名稱
別 名 HA synthase 3; HAS3; HAS 3; HAS-3; HAS3_HUMAN; Hyaluronan synthase 3; Hyaluronate synthase 3; Hyaluronic acid synthase 3.
研究領域 神經生物學 信號轉導 干細胞 細胞骨架 細胞外基質
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 61kDa
細胞定位 細胞膜
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human HAS3
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
公司更多相關產品:
YMK-1798R *受體2抗體 Anti-GLUR2
YMK-2175R *受體1抗體 Anti-NR1/NMDAR1
YMK-12175R 電壓門控性鉀通道蛋白亞基KV6.3抗體 Anti-KCNG3
YMK-2030R 天冬氨酸受體抗體 Anti-NMDA-NR1/NR1/NMDAR1
YMK-12030R G蛋白偶聯受體33抗體 Anti-GPCR6A/GPCR33
YMK-11068R 腱糖蛋白R抗體 Anti-TNR/Tenascin R/TENR
YMK-1068R *受體1抗體 Anti-NMDA-NR1/NR1/NMDAR1
YMK-2184R 醌氧化還原酶抗體 Anti-NQO1
YMK-12184R 電壓門控性鉀通道Kv1.6抗體 Anti-Kv1.6
YMK-1070R 神經肽Y1受體抗體 Anti-NPY1R
YMK-11070R 粘附分子IgG樣結構域蛋白1抗體 Anti-AMIGO1
YMK-0937R 神經肽Y受體2抗體 Anti-NPY2R
YMK-10071R 血管內皮生長因子B167抗體 Anti-VEGFB167
YMK-0071R 神經肽Y抗體 Anti-NPY/Neuropeptide Y
YMK-0353R 壬基酚抗體 Anti-Nonylphenol
YMK-10353R 磷酸化非受體*激酶c-Abl抗體 Anti-phospho-c-ABL(Tyr204)
YMK-1069R 促尿鈉排泄肽前體C抗體 Anti-proCNP/NPPC
YMK-11069R Ⅱ型膠原α1 N端前體肽抗體 Anti-procollagen type IIA
YMK-1537R 還原型輔酶Ⅱ/磷酸酰胺腺嘌呤二核苷酸抗體 Anti-NADPH
YMK-11537R 小腦肽3抗體 Anti-CBLN3/Cerebellin 3