上海研盟生物有限公司*品質供應Anti-KCNMB1抗體，我公司銷售國內外科研產品，如生物試劑、生化試劑，一抗二抗，各種標記抗體，Elisa酶聯免疫試劑盒，放免試劑盒，培養基，各種動物血清等產品，歡迎廣大新老客戶前來咨詢訂購，訂購:或。

鈣激活鉀通道蛋白β1抗體,Anti-KCNMB1抗體簡單介紹：

中文名稱：鈣激活鉀通道蛋白β1抗體

英文名稱：Anti-KCNMB1抗體

別 名：MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits; KCMB1_HUMAN.  

此產品本公司有標記的一抗出售，相關標記有：Alexa Fluor 350 標記、Alexa Fluor 488 標記、Alexa Fluor 555 標記、Alexa Fluor 647 標記、AP標記、APC標記、Biotin標記、Cy3標記、Cy5標記、Cy5.5標記、Cy7標記、FITC標記、Gold標記、HRP標記、PE標記、PE-Cy3標記、PE-CY5標記、PE-CY5.5標記、PE-CY7標記、RBITC標記

背景介紹：Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation. 

規格：0.1ml/0.2ml

濃度：1mg/1ml

抗體來源：本公司抗體有兔來源和鼠來源等

克隆類型：兔來源為多抗，鼠來源為單抗

產品類型：一抗

鈣激活鉀通道蛋白β1抗體保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

避免反復凍融，保質期一年。

鈣激活鉀通道蛋白β1抗體,Anti-KCNMB1抗體免疫組化問題解答

1、染色過強？

原 因：抗體濃度過高或孵育時間過長

解決方法：降低抗體滴度、抗體孵育時間：室溫1小時或4度過夜

原 因：孵育溫度過高超過37度

解決方法：一般在室溫20-28度

原 因：DAB顯色時間過長或濃度過高

解決方法：顯色時間不超過5-12分鐘，以顯微鏡下觀察為準

2、非特異性背景染色？

原 因：操作過程中沖洗不充分

解決方法：每步沖洗3次每次5分鐘

原 因：組織中含過氧化物酶未阻斷

解決方法：可再配置新鮮3%H2O2封閉孵育時間延長

原 因：組織中含內原性*

解決方法：正常非免疫動物血清再封閉

原 因：血清蛋白封閉不充分

解決方法：血清蛋白封閉不充分

鈣激活鉀通道蛋白β1抗體,Anti-KCNMB1抗體相關優質產品：

SSTR1 (somatostatin receptor 1)  *受體1(SSTR1)抗體
SSTR2 (somatostatin receptor 2)  *受體2抗體
SSTR3 (somatostatin receptor 3)  *受體3抗體
SSTR4(somatostatin receptor 4)  *受體4抗體
SSTR5 (somatostatin receptor 5)  *受體5抗體
STAT1（signal transduceBYK and activatoBYK of transcription 1）  信號轉導與轉錄激活因子1抗體
phospho-STAT1(p-Tyr701)  抗磷酸化信號轉導與轉錄激活因子1抗體
STAT2 (signal transduceBYK and activatoBYK of transduction2)  信號轉導和轉錄激活因子2(STAT2)抗體
STEAP1（Six transmbrane epithelial antigen of the prostate 1）  前列腺跨膜上皮1抗原抗體
phospho-STAT3(pThr705)  抗磷酸化信號轉導和轉錄激活因子3抗體
phospho-STAT5a(pThr694)  抗磷酸化信號轉導和轉錄激活因子5a抗體
phospho-STAT6(pThr641)  抗磷酸化信號轉導和轉錄激活因子6抗體
STAT3 (signal transduceBYK and activatoBYK of transduction 3)  信號轉導和轉錄激活因子3抗體
STAT4 (signal transduceBYK and activatoBYK of transduction 4)  信號轉導和轉錄激活因子4抗體
STAT5 (signal transduceBYK and activatoBYK of transduction 5)  信號轉導和轉錄激活因子5(STAT5)抗體
STAT6 (signal transduceBYK and activatoBYK of transduction 6)  信號轉導和轉錄激活因子6抗體
Stra8(Stimulated by retinoic acid gene 8)  *激活基因8抗體
STRO-1  一種間充質干細胞抗體
streptomycin  *抗體