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中文名稱：宮頸黏液蛋白相關蛋白抗體

英文名稱：Anti-HIP55 antibody

上海研盟生物科技有限公司Anti-HIP55抗體*，主要應用于WB、IHC、IF、ELISA、流式細胞術等實驗中。說明書隨貨發送，您也可以直接我司在線客服索取。客服:.

宮頸黏液蛋白相關蛋白抗體,Anti-HIP55抗體簡單介紹：

產品別名：ABP1; Actin-binding protein 1; Cervical mucin associated protein; Cervical mucin-associated protein; Cervical SH3P7; CMAP; Dbnl; DBNL_HUMAN; Drebrin F; drebrin like; Drebrin like protein; Drebrin-F; Drebrin-like protein; HIP 55; HIP-55; HPK1 interacting protein of 55 kDa; HPK1-interacting protein of 55 kDa; SH3 domain containing protein 7; SH3 domain-containing protein 7; SH3P7; Src Homology 3 Domain Containing Protein; src homology 3 domain containing protein HIP.

產品規格：0.1ml、0.2ml、1ml

產品用途：科研實驗

產品價格：請報價

說明書：請添加客服直接索取

抗體來源：該指標有兩種產品，一種是兔來源抗體，一種是鼠來源抗體

克隆類型：兔來源為多克隆抗體，鼠來源單克隆抗體

交叉反應：請索取說明書查看

背景介紹：Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. HIP-55 (HPK1-interacting protein of 55 kDa), also known as ABP1, SH3P7 or DBNL (drebrin-like), is a 430 amino acid cytoplasmic protein that belongs to the ABP1 family. HIP-55 binds to F-actin but is not involved in actin polymerization, capping or bundling. In addition to containing an ADF-H domain, HIP-55 also consists of a SH3 domain, which mediates interaction with SHANK2, SHANK3 and PRAM-1. HIP-55 acts as an actin-binding adapter protein and as a common effector of antigen receptor-signaling pathways in leukocytes. As a key component of the immunological synapse, HIP-55 regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. HIP-55 is degraded by caspases during apoptosis.

宮頸黏液蛋白相關蛋白抗體保存條件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

性狀：Lyophilized or Liquid

濃度：1mg/1ml

亞型:IgG

純化方法: affinity purified by Protein A

儲存液: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol

免疫應答過程：

1.抗原進入機體；

2.抗原刺激 B淋巴細胞，使之分化增殖成為抗體分泌漿細胞和記憶細胞（初次免疫應答）；

3.抗體主要由漿細胞分泌；

4.記憶細胞再次受到特異性抗原刺激后會被激活而成為分泌抗體的漿細胞（再次免疫應答）；

5.記憶B細胞是長命細胞，可以存活數月甚至機體終生。

初次體液免疫是指宿主*次接觸外來TD抗原后血清中逐漸出現抗原特異性抗體的過程。初次體液免疫應答的延遲相（從抗原免疫到抗體水平達到高峰的時間）為6-10天，起初幾天血清中的抗原特異性抗體主要為親和力較低的IgM,后期以IgG為主。初次應答過程的血清中抗原特異性抗體的高峰濃度較低且維持時間較短。再次體液免疫應答是指曾被某抗原免疫過的宿主再次接觸該抗原時血清中迅速出現抗原特異性抗體的過程，其延遲相僅為4-5天，血清抗體以IgG為主，其高峰濃度較高且維持時間較長。再次應答所產生的抗體還有親和力成熟現象，即該抗體與抗原的親和力明顯高于初次應答產生的抗體。

宮頸黏液蛋白相關蛋白抗體,Anti-HIP55抗體相關產品：

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Histone H3-like protein  組蛋白H3樣抗體(Brassica juncea)
Histone H3-like protein  組蛋白H3樣抗體（Brassica junceaC端抗體）
Histone H3-like protein  組蛋白H3樣蛋白抗體（Brassica juncea N端抗體）