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上海研盟生物科技有限公司
“Anti-APOE抗體,載脂蛋白E抗體“抗體規格0.1ml、0.2ml、1ml,抗體產品有效期一年,質保三個月,質保期內出現任何質量問題或是出不了實驗結果均可免費退換:
上海研盟生物科技有限公司Anti-APOE抗體,載脂蛋白E抗體*,主要應用于WB、IHC、IF、ELISA、流式細胞術等實驗中。說明書隨貨發送,您也可以直接我司在線客服索取。客服
簡單介紹:
中文名稱:載脂蛋白E抗體
英文名稱:Anti-APOE
產品編號:byk-0167R
產品別名:Apolipoprotein E precursor; AD2; Alzheimer disease 2; Apo E; ApoE; APOEA; ApolipoproteinE; Apolipoprotein-E; Apoprotein; MGC1571; Apo E2; ApoE2; APOE 2; Apolipoprotein E2; LDLCQ5; LPG; APOE_HUMAN; Apo-E.
產品用途:科研實驗
產品價格:請報價
說明書:請添加客服直接索取
抗體來源:該指標有兩種產品,一種是兔來源抗體,一種是鼠來源抗體
克隆類型:兔來源為多克隆抗體,鼠來源單克隆抗體
交叉反應:請索取說明書查看
性 狀:Lyophilized or Liquid
濃 度:1mg/1ml
亞 型:IgG
純化方法: affinity purified by Protein A
儲 存 液: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-APOE抗體,載脂蛋白E抗體產品介紹:Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol and triglycerides levels which are the consequence of impaired clearance of chylomicron and VLDL remnants.
Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
免疫組化的呈色深淺可反映抗原存在的數量,可作為定性、定位和定量的依據。
1.陽性細胞染色分布有三種類型:細胞漿、細胞核、細胞膜表面。大部分抗原見于細胞漿,可見于整個胞漿或部分胞漿
2.陽性細胞分布可分為灶型和彌漫性
3.由于細胞內含抗原量不同,所以染色強度不一。如果細胞之間染色強度相同,常提示其反應為非特異性
4.陽性細胞染色定位于單個細胞,且與陰性細胞相互交雜分布;而非特異性染色常不限于單個細胞,而是累及一片細胞。
5.切片邊緣、刀痕或褶皺區域,壞死或擠壓的細胞區,膠原結締組織等,常表現為相同的陽性染色強度,不能用于判斷陽性。
相關產品:
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Langerin/CD207/CLEC4K(C-type lectin domain family 4 member K) 白細胞分化抗原CD207抗體
LAP18/stathmin(leukemia associated protein 18) 白血病相關蛋白18/癌蛋白18抗體
LAT/LAT1(Linker for activation of T cell 1) T細胞活化連接蛋白
LAIR-1/CD305(Leukocyte-associated immunoglobulin-like receptor 1) 白細胞相關免疫球蛋白樣受體1抗體
Layilin 透明質酸受體抗體
LAIR-2/CD306(Leukocyte-associated immunoglobulin-like receptor 2) 白細胞相關免疫球蛋白樣受體2抗體
LCAT(lecithin cholesterol acyl transferase) 卵磷*酰基轉移酶抗體
L-Citrulline 抗L-瓜氨酸抗體
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LDL-R (Low-density lipoprotein receptor precuBYKor) 低密度脂蛋白受體抗體
ox-LDL(Cu2SO4 oxidized low density lipoprotein) 抗氧化低密度脂蛋白抗體
LDH(Lactate DeYMdrogenase) 抗乳酸脫氫酶抗體
Lectin (Mannan-binding lectin; L-MBP) 抗凝集素抗體
LEF-1(lymphoid enhancing factor-1) 淋巴增強因子-1抗體
Leptin 瘦素抗體
Leptin 瘦素抗體
Leptin R(Leptin receptor) 瘦素受體抗體
Leptin receptor(long) 瘦素受體抗體(長)
Leptin receptor(long) 瘦素受體抗體(長)
Leptin receptor(L、M、S) 瘦素受體抗體(長、中、短型)
L-enk 抗*腦啡肽抗體
Lgr5/GPR49(G protein coupled receptor 49) Lgr5/GPR49抗體
LH (Human Luteinizing Hormone) mouse monoclonal antibody 鼠抗促黃體生成素抗體
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