RESOMER 是贏創(chuàng)旗下一系列生物可降解聚合物的商品名。這類聚合物由丙交酯和乙交酯聚合而成。通過調(diào)整分子量，單體比例或加入其它單體，在植入或注射后在人體組織內(nèi)按照一定速率降解。體液能將聚合物水解為低聚體甚至為羥基酸單體，Z終為人體代謝。RESOMER®在多種應(yīng)用中均表現(xiàn)出了良好的生物相容性：例如：整形外科固定件，提供粉末形態(tài)供藥物制劑使用。RESOMER穩(wěn)定性考察表明聚合物在合適的條件下能*存

詳細(xì)介紹

關(guān)鍵字：RESOMER 生物可降解聚合物

RESOMER 是贏創(chuàng)旗下一系列生物可降解聚合物的商品名。這類聚合物由丙交酯和乙交酯聚合而成。通過調(diào)整分子量，單體比例或加入其它單體，在植入或注射后在人體組織內(nèi)按照一定速率降解。體液能將聚合物水解為低聚體甚至為羥基酸單體，zui終為人體代謝。RESOMER®在多種應(yīng)用中均表現(xiàn)出了良好的生物相容性：例如：整形外科固定件，提供粉末形態(tài)供藥物制劑使用。RESOMER穩(wěn)定性考察表明聚合物在合適的條件下能*存放。

具體產(chǎn)品如下：

名稱	分子量	粘性	用途	Tg [℃]	Tm [℃]	末端基
RESOMER L 206 S Poly(L-lactide)	--	0.8 - 1.2	Medical Device	60 - 65	180 - 185	alkyl ester
RESOMER R 202 S Poly(D,L-lactide)	10,000 - 18,000	0.16 - 0.24	Controlled Release	38 - 42	amorphous	alkyl ester
RESOMER R 202 H Poly(D,L-lactide)	10,000 - 18,000	0.16 - 0.24	Controlled Release	44 - 48	amorphous	free carboxylic acid
RESOMER R 203 S Poly(D,L-lactide)	18,000 - 28,000	0.25 - 0.35	Controlled Release	46 - 50	amorphous	Alkyl ester
RESOMER R 203 H Poly(D,L-lactide)	18,000 - 28,000	0.25 - 0.35	Controlled Release	48 - 52	amorphous	free carboxylic acid
RESOMER RG 502 Poly(D,L-lactide-co-glycolide) 50:50	7,000 - 17,000	0.16 - 0.24	Controlled Release	42 - 46	amorphous	alkyl ester
RESOMER RG 502 H Poly(D,L-lactide-co-glycolide) 50:50	7,000 - 17,000	0.16 - 0.24	Controlled Release	42 - 46	amorphous	free carboxylic acid
RESOMER RG503 Poly(D,L-lactide-co-glycolide) 50:50	24,000 - 38,000	0.32 - 0.44	Controlled Release	-	amorphous	alkyl ester
RESOMER RG 503 H Poly(D,L-lactide-co-glycolide) 50:50	24,000 - 38,000	0.32 - 0.44	Controlled Release	44 - 48	amorphous	free carboxylic acid
RESOMER RG504 Poly(D,L-lactide-co-glycolide) 50:50	38,000 - 54,000	0.45 - 0.60	Controlled Release	-	amorphous	alkyl ester
RESOMER RG 504 H Poly(D,L-lactide-co-glycolide) 50:50	38,000 - 54,000	0.45 - 0.60	Controlled Release	46 - 50	amorphous	free carboxylic acid
RESOMER RG505 Poly(D,L-lactide-co-glycolide) 50:50	54,000 - 69,000	0.61 - 0.74	Controlled Release	-	amorphous	alkyl ester
RESOMER RG 653 H Poly(D,L-lactide-co-glycolide) 65:35	24,000 - 38,000	0.32 - 0.44	Controlled Release	46 - 50	amorphous	free carboxylic acid
RESOMER RG 752 H Poly(D,L-lactide-co-glycolide) 75:25	4,000 - 15,000	0.14 - 0.22	Controlled Release	42 - 46	amorphous	free carboxylic acid
RESOMER RG 756 S Poly(D,L-lactide-co-glycolide) 75:25	76,000 - 116,000	0.71 - 1.0	Controlled Release	49 - 55	amorphous	alkyl ester
RESOMER RG858 S Poly(D,L-lactide-co-glycolide) 85:15	190,000 - 240,000	1.3 - 1.7	Controlled Release	-	amorphous	alkyl ester
RESOMER X Polydioxanone	--	1.5 - 2.2 (0.1% in HFIP, 30℃)	Medical Device	-10 - -5	110 - 115	--