Iscove's Modified Dulbecco's Medium (IMDM) is well suited for rapidly proliferating, high-density cell cultures, including Jurkat, COS-7, and macrophage cells. We offer a variety of Gibco™ IMDM modifications for a range of cell culture applications. Find the right formulation using the media selector tool.
This IMDM is modified as follows:
| With | Without |
| • GlutaMAX™ | • α-thioglycerol |
The complete formulation is available.
IMDM, a modification of Dulbecco's Modified Eagle Medium, includes selenium as well as additional amino acids and vitamins. In addition, this unique medium lacks iron, with potassium nitrate replacing ferric nitrate. Gibco™ IMDM with GlutaMAX™ supplement minimizes toxic ammonia build-up and improves cell viability and growth in an easy-to-use format.
cGMP Manufacturing and Quality SystemGibco™ IMDM is manufactured at a cGMP compliant facility, located in Paisley, Scotland, UK. The facility is registered with the FDA as a medical device manufacturer and is certified to the ISO 13485 standard. For supply chain continuity, we offer an identical Gibco™ IMDM product made in our Grａnd Islａnd facility (31980-097). This facility is registered with the FDA as a medical device manufacturer and is certified to the ISO 13485 standards.
IMDM contains no proteins, lipids, or growth factors. Therefore, IMDM requires supplementation, commonly with 10% Fetal Bovine Serum (FBS). IMDM uses a sodium bicarbonate buffer system (3.024 g/L) and therefore requires a 5-10% CO
2 environment to maintain physiological pH.
