日韩午夜在线观看,色偷偷伊人,免费一级毛片不卡不收费,日韩午夜在线视频不卡片

上海懋康生物科技有限公司
中級會員 | 第9年

18616957973

當前位置:上海懋康生物科技有限公司>>信號轉導研究相關>>Wnt/Hedgehog (Hh)/ Notch信號通路>> 04-0004Stemolecule™ CHIR99021(GSK-3β抑制劑) 生化試劑

Stemolecule™ CHIR99021(GSK-3β抑制劑) 生化試劑

參   考   價: 11

訂  貨  量: ≥1  臺

具體成交價以合同協議為準

產品型號04-0004

品       牌其他品牌

廠商性質生產商

所  在  地上海市

更新時間:2023-02-15 15:31:58瀏覽次數:762次

聯系我時,請告知來自 環保在線
分類 其他 級別 其他
Stemolecule™ CHIR99021(GSK-3β抑制劑):氨基嘧啶CHIR99021是目前為止報道的選擇性Z強的GSK-3β抑制劑。與其他強效的GSK-3抑制劑相比,CHIR99021不會交叉抑制細胞周期蛋白依賴性激酶(CDKs),對GSK-3β的選擇性是對CDKs的350倍。

Stemolecule™ CHIR99021GSK-3β抑制劑)


產品關鍵詞:

GSK-3βna?ve stem cells 初始干細胞;neural progenitor cells 神經祖細胞;WH-4-023Y27632PD0325901CAS252917-06-9


產品描述:

氨基嘧啶CHIR99021是目前為止報道的選擇性zui強的GSK-3β抑制劑。與其他強效的GSK-3抑制劑相比,CHIR99021不會交叉抑制細胞周期蛋白依賴性激酶(CDKs),對GSK-3β的選擇性是對CDKs350倍。與抑制MAPK來源的分化誘導信號聯合,使用CHIR99021阻斷 GSK-3β信號使得胚胎干細胞能自我更新。


產品特性

  1. 同義名:6-[[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2 pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile

  2. 分子式:C22H18Cl2N8

  3. 分子量:465.34 g/mol

  4. CAS NO252917-06-9

  5. 純度:>95%HPLC

  6. 外觀:Off-white solid

  7. 溶解性:DMSO

  8. 保存和穩定性:粉末4 °C避光保存,重溶后的儲存液分裝后-20 °C保存,6個月穩定。

  9. 質量控制:HPLC測定純度,MS測定準確分子量,CHIR99021對小鼠胚胎干細胞的細胞毒性測試。

  10. 結構圖:


訂購信息:原裝好貨,歡迎訂購,:

品牌

名稱

貨號

規格

Stemgent

Stemolecule™ CHIR99021

04-0004

2 mg

Stemgent

Stemolecule™ CHIR99021

04-0004-10

10 mg

Stemgent

Stemolecule™ CHIR99021

04-0004-02

2 mg (10 mM)


引用文獻:

  • Xia N; Zhang P; Fang F; Wang Z; Rothstein M; Agulo B; Chiang R; Taylor J; Reijo Pera RA. "Transcriptional comparison of human induced and primary midbrain dopaminergic neurons." Scientific Reports. 6:20270. doi:10.1038/srep20270 (2016)

  • Han Y-C, Lim Y; Duffieldl MD; Liu J; Manaph NPA; Yang M; Keating DJ; Zhou X-F. "Direct reprogramming of mouse fibroblasts to neural stem cells by small molecules." Stem Cells International 2016:4304916 (2016)

  • Zhu S; Russ HA; Wang X; Zhang M; Ma T; Xu T; Tang S; Hebrok M; Deng S. "Human pancreatic beta-like cells converted from fibroblasts." Nature Commun 7:10080 (2016)

  • Titmarsh DM; Glass NR; Mills RJ; Hidalgo A; Volvetang EJ; Porrello ER; Hudson JE; Cooper-White JJ. "Induction of human iPSC-derived cardiomyocyte proliferation revealed by combinatorial screening in high density microbioreactor arrays." Sci Rep 6:24637 (2016)

  • Liu G. "No detection of potential cancer risk for free-viral reprogrammed stem cell-derived dopaminergic neurons from adult mice fibroblasts." J Stem Cell Res Ther 5:286 (2015)

  • Fonoudi H; Ansari H; Abbasalizadeh S; Laruani MR; Kiani S; Hashemizadeh S; Zarchi AS; Bosman A; Blue GM; Pahlavan S; Perry M; Orr Y; Mayorchak Y; Vandenberg J; Talkhabi M; Winlaw SD; Harvey RP; Aghdami N; Baharvand H. "A universal and robust integrated platform for the scalable production of human coardiomhyocytes from pluripotent stem cells." Stem Cells Trans Med 4:1482 (2015)

  • Yang J; Kaur K; Ong LL; Eisenberg CA; Eisenberg LM. "Inhibition of G9a histone methyltransferase converts bbone marrow mesenchymal stem cells to cardiac competent progenitors." Stem Cells International Article 270428 (2015) doi:10.1155/2015/270428

  • Ren J; Briones V; Barbour S; Yu W; Han Y; Tarashima M; Muegge K. "The ATP binding site of the chromatin remodeling homolog LSH is required for nucleosome density and de novo DNA methylation at repeat sequences." Nucl Acids Res doi: 10.1093/nar/gku1371 (2015)

  • DeRosa BA; Belle KC; Thomas BJ; Cukier HN; Pericak-Vance MA; Vance JM; Dykxhoom DM. "hVGAT-mCherry: A novel molecular tool for analysis of GABAergic neurons derived from human pluripotent stem cells." Mol Cell Neurosci 68:244 (2015)

  • Tan H-K; Toh C-XDl Ma D; Yang B; Liu TM; Lu J; Wong C-W; Tan T-K; Li H; SYn C; Tan E-L; Lim B; Lim Y-P; Cook SA; Loh Y-H. "Human finger-prick induced pluripotent stem cells facilitate the development of stem cell banking." Stem Cells Trans Medicine 3:586 (2014)

  • Ying, Q., Tai, C. Gbx2, a LIF/Stat3 target, promotes reprogramming to and retention of the pluripotent ground state. Journal of Cell Science 126, 1093 – 1098.(2013)

  • Youn H; Kim S-H; Choi KA; Kim S. "Characterization of Oct4-GFP spermatogonial stem cell line and its applicationo in the reprogramming studies." J Cell Biochem 114:920 (2013)

  • Blauwkamp TA; Nigam S; Ardehali R; Weissman IL; Nusse R. Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors. Nature Communications 3:1070 (2012).

  • Lian, X., Hsiao, C., Wilson, G, Zhu, K., Hazeltine, L.B., Azarin, S.M., Raval, K.K., Zhang, J., Kamp, T.J., and Palecek, S.P. (2012) Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling. Proc Natl Acad Sci USA 109: E1848 (2012)

  • Moraveji S-F; Attari F; Shahverdi A; Sepehri H; Farrokhi A; Hassani S; Fonoudi H; Aghdami N; Baharvand H. "Inhibition of glycogen synthase kinase-3 promotes efficient derivation of pluripotent stem cells from neonatal mouse testis." Human Reproduction 27:2312 (2012)

  • Nagy, K., Sung, H-K., Zhang, P., Laflamme, S., Vincent, P, Agha-Mohammadi, S., Woltjen, K., Monetti, C., Michael, I. P., Smith, L. C., Nagy, A. Induced Pluripotent Stem Cell Lines Derive from Equine Fibroblasts. Stem Cell Reviews and Reports 7:693 (2011).

  • Wang, B., Miyagoe-Suzuki, Y., Yada, E., Ito, N., Nishiyama, T., Nakamura, M., Ono, Y., Motohashi, N., Segawa, M., Masuda, S., Takeda, S. Reprogramming Efficiency and Quality of Induced Pluripotent Stem Cells (iPSCs) Generated from Muscle-derived Fibroblasts of MDX Mice at Different Ages. PLOS Currents Muscular Dystrophy. 2011 Oct 27 . Edition 1. doi: 10.1371/currents.RRN1274 .

  • Mack, A., Kroboth, S., Rajesh, D., Wang, W. B. Generation of Induced Pluripotent Stem Cells from CD34+ Cells across Blood Drawn from Multiple Donors with Non-Integrating Episomal Vectors. PLoS One; 6(11): e27956.(2011)

  • Li, W., Zhou, H., Abujarour, R., Zhu, S., Young Joo, J., Lin, T., Hao, E., Sch?ler, H.R., Hayek, A., Ding, S. (2009) Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2. Stem Cells 27: 2992-3000.

  • Chiang P-M; Wong PC. "Differentiation of an embryonic stem cell to hemogenic endothelium by defined factors: Essential role of bone morphogenetic protein 4." Development 138: 2833-2843 (2011)


— —Written/Edited by V. Shallan【版權歸MKBio懋康所有】


上海懋康生物科技有限公司是一家涉足于生命科學和生物技術領域研究的試劑、儀器和實驗室消耗品與實驗服務工作,主要從事細胞生物學、植物學、分子生物學、免疫學、生物化學、蛋白組學。生物制藥與診斷試劑研發生產等領域。 本公司秉承以人為本,以誠為信、合同守信"的經營理念。堅持"品質保障"的原則為廣大客戶提供優質產品。


Stemolecule™ CHIR99021(GSK-3β抑制劑)

Stemolecule™ CHIR99021(GSK-3β抑制劑)

Stemolecule™ CHIR99021(GSK-3β抑制劑)


會員登錄

×

請輸入賬號

請輸入密碼

=

請輸驗證碼

收藏該商鋪

X
該信息已收藏!
標簽:
保存成功

(空格分隔,最多3個,單個標簽最多10個字符)

常用:

提示

X
您的留言已提交成功!我們將在第一時間回復您~
撥打電話
在線留言
主站蜘蛛池模板: 江永县| 偃师市| 潢川县| 江华| 尼玛县| 安西县| 舟曲县| 甘洛县| 利川市| 马边| 金溪县| 开封县| 哈密市| 左云县| 南投县| 巴楚县| 绥宁县| 达尔| 榆中县| 大厂| 随州市| 静安区| 文成县| 南康市| 通州区| 牡丹江市| 泰安市| 青岛市| 定兴县| 鹤壁市| 得荣县| 社旗县| 井冈山市| 山东省| 年辖:市辖区| 光山县| 屏东市| 永德县| 大理市| 伊川县| 张北县|