Anti-HDAC1/HD1 組蛋白去乙酰化酶1抗體
專業提供Anti-HDAC1/HD1 組蛋白去乙酰化酶1抗體,廣泛應用于免疫組化，ELISA，Western Blot IHC-F（免疫組化－冰凍切片），IHC-P （免疫組化－石蠟切片）IP（免疫沉淀）， Flow-Cyt等方面。
產品編號 Rs-1414R
英文名稱 Anti-HDAC1/HD1
中文名稱 組蛋白去乙酰化酶1抗體
抗體介紹：Reversible acetylation of highly conserved lysine residues within the N-terminal tail domains of core histones, plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation is a dynamic process determined by the net activities of histone acetyltransferases （HATs） and the competing enzymes histone deacetylases （HDACs）. Histone deacetylases activities are often, but not always, associated with transcriptional repression and nucleosomal condensations. Recruitment of the multiprotein complexes to promoter sites occurs by many sequence specific DNA-binding proteins such as unliganded nuclear hormone receptors, DP1-E2F, YY1 and Rb family of transcription factors, transcriptional repressors and tumor suppressors （e.g. BRCA1）. Aberrant recruitment of HDACs by certain oncoproteins may occur in certain neoplastic diseases. Belongs to the histone deacetylase family. Type 1
別 名 DKFZp686H12203; GON 10; HD 1; HD1; HDAC 1; hdac1: histone deacetylase 1; Histone deacetylase 1 （HD1）; Histone deacetylase 1; RPD3 （reduced potassium dependency yeast homolog） like 1; RPD3 （reduced potassium dependency）; RPD3; RPD3L1.
產品類型 一抗
抗體來源 Rabbit
克隆號 Polyclonal
交叉反應 hu, mo, rat, pig, Rb, Gpig
蛋白分子量 Predicted Molecular Weight: 53kDa
性狀 Lyophilized or Liquid
濃度 1mg/1ml
免疫原 KLH conjugated synthetic peptide derived from human HDAC1 C-terminus.
亞型 IgG
產品應用 WB=1:100-500 Elisa=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1/20-1/100
（石蠟切片需做抗原修復）Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
研究領域 腫瘤 發育生物學 轉錄調節因子
公司提供的.已被國內外廣大科研工作者使用，廣泛用于分子生物學、免疫學等試驗中。
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