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聯(lián)系我時,請告知來自 環(huán)保在線Anti-Phospho-Histone H3 (Thr11)磷酸化組蛋白H3抗體, 四種組蛋白(H2A、H2A、H3、H4)氨基酸序列都非常相似, 如海膽組織H3的氨基酸序列與來自小牛胸腺的H3的氨基酸序列間只有一個氨基酸的差異, 小牛胸腺的H3的氨基酸序列與豌豆的H3也很相似
Anti-Phospho-Histone H3 (Thr11)磷酸化組蛋白H3抗體
專業(yè)提供Anti-Phospho-Histone H3 (Thr11)磷酸化組蛋白H3抗體 廣泛應用于免疫組化,ELISA,Western Blot IHC-F(免疫組化-冰凍切片),IHC-P (免疫組化-石蠟切片)IP(免疫沉淀), Flow-Cyt等方面。
產(chǎn)品編號 Rs-3188R
英文名稱 Anti-Phospho-Histone H3 (Thr11)
中文名稱 磷酸化組蛋白H3抗體
抗體介紹:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximay 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fibre is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. Covalent modifications of the canonical core histones, including acetylation, phosphorylation, methylation, and monoubiquitination are used to mark nucleosomes to create chromatin domains with a range of functions. The information encoded by histone modifications can contribute to the formation and/or maintenance of transcriptionally active and inactive chromatin in response to various signalling pathways.
別 名 H3 histone family member E pseudogene; H3F3; HIST3H3; Histone H3 3 pseudogene.
產(chǎn)品類型 一抗
抗體來源 Rabbit
克隆號 Polyclonal
交叉反應 hu, rat, mo
蛋白分子量 Predicted Molecular Weight: 15kDa
性狀 Lyophilized or Liquid
濃度 1mg/1ml
免疫原 KLH conjugated Synthesised phosphopeptide derived from human Histone H3 around the phosphorylation site of Thr11.
亞型 IgG
純化方法 affinity purified by Protein A
儲存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用 WB=1:100-500 Elisa=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1/20-1/100
(石蠟切片需做抗原修復)Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
研究領域 腫瘤 免疫學 染色質(zhì)和核信號 信號轉(zhuǎn)導 轉(zhuǎn)錄調(diào)節(jié)因子
保存 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
公司提供的已被國內(nèi)外廣大科研工作者使用,廣泛用于分子生物學、免疫學等試驗中。
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