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Anti-ELAVL4/HuD抗體,ELAVL4蛋白抗體-技術(shù)指導(dǎo)

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商鋪產(chǎn)品:9977條

所在地區(qū):上海上海市

聯(lián)系人:楊洋 (經(jīng)理)

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博研生物強(qiáng)烈*“Anti-ELAVL4/HuD抗體,ELAVL4蛋白抗體-技術(shù)指導(dǎo)",品質(zhì)保障,*,提供,實(shí)驗(yàn)無結(jié)果可免費(fèi)退換!:

詳細(xì)介紹

Anti-ELAVL4/HuD抗體,ELAVL4蛋白抗體-技術(shù)指導(dǎo)產(chǎn)品介紹:The Elav-like genes encode for a family of RNA-binding proteins. Elav, a Drosophila protein and the first described member, is expressed immediay after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance. Several mammalian Elav-like proteins, designated HuC, HuD and Hel-N1, are also expressed in postmitotic neurons. An additional mammalian homolog, HuR, which is also designated HuA, is ubiquitously expressed and is also overexpressed in a wide variety of tumors. Characteristically, these homologs all contain three RNA recognition motifs (RRM) and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts. ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cell growth and differentiation. When Elav-like proteins associate with these ARE sites this degradation is inhibited, leading to an increased stability of the corresponding transcript. Elav proteins function within the nucleus, and they are shuttled between the nucleus and cytoplasm by a nuclear export signal, which is a regulatory feature of the Elav-like proteins as it limits their accessibility to ARE sites.

保存條件:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃

重要提示: 本產(chǎn)品提供僅供研究使用,不用于人類治療或診斷.


產(chǎn)品名稱:Anti-ELAVL4/HuD抗體,ELAVL4蛋白抗體-技術(shù)指導(dǎo)

產(chǎn)品編號(hào):BYK-11319R

產(chǎn)品規(guī)格:0.1ml/0.2ml

產(chǎn)品價(jià)格:請(qǐng)

性 狀:Lyophilized or Liquid

濃 度:1mg/1ml

亞 型:IgG

貯 存:貯存于-20℃.

抗體來源:本公司抗體有兔來源和鼠來源等

克隆類型:兔來源為多抗,鼠來源為單抗

產(chǎn)品類型:一抗

此抗體本公司有單抗和多抗,可用于免疫組化(IHC),免疫印跡(WB),酶聯(lián)免疫(ELISA),IF、IP、流式細(xì)胞術(shù)等實(shí)驗(yàn)(可來電索取說明)

此產(chǎn)品本公司有標(biāo)記的一抗出售,相關(guān)標(biāo)記有:Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記


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