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Anti-lamin A/C抗體,核纖層蛋白A/C抗體

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博研生物強(qiáng)烈*“Anti-lamin A/C抗體,核纖層蛋白A/C抗體",品質(zhì)保障,*,提供,實(shí)驗(yàn)無結(jié)果可免費(fèi)退換!:

詳細(xì)介紹

Anti-lamin A/C抗體,核纖層蛋白A/C抗體產(chǎn)品介紹:An important part of the cell nucleus is formed by nuclear lamina. Nuclear lamins form a network of filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. 
The nuclear lamins comprise a unique subclass of the intermediate filament protein family. They share a molecular domain organisation with the other intermediate filament proteins in that they are fibrous molecules that have an aminoterminal globular head, a central rod of a-helices and a carboxyterminal globular domain. 
Many biochemical and molecular features of lamins have been studied, but their functions remain still largely undetermined. One of the functions ascribed to the lamina is the maintenance of the structural integrity of the nucleus. 
Besides interactions with the nuclear membrane and other intermediate filaments, lamins interact with the nuclear chromatin. Eukaryotic chromatin is organised into loops, which are attached to the nuclear matrix. This organisation is thought to contribute to compaction of the chromatin and regulation of gene expression. Lamins, as part of the nuclear matrix, may be involved in these processes since chromatin binding sites have been detected in both A- and B-type lamins.

保存條件:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃

重要提示: 本產(chǎn)品提供僅供研究使用,不用于人類治療或診斷.


產(chǎn)品名稱:Anti-lamin A/C抗體,核纖層蛋白A/C抗體

產(chǎn)品編號(hào):BYK-1841R

產(chǎn)品規(guī)格:0.1ml/0.2ml

產(chǎn)品價(jià)格:請(qǐng)

性 狀:Lyophilized or Liquid

濃 度:1mg/1ml

亞 型:IgG

貯 存:貯存于-20℃.

抗體來源:本公司抗體有兔來源和鼠來源等

克隆類型:兔來源為多抗,鼠來源為單抗

產(chǎn)品類型:一抗

此抗體本公司有單抗和多抗,可用于免疫組化(IHC),免疫印跡(WB),酶聯(lián)免疫(ELISA),IF、IP、流式細(xì)胞術(shù)等實(shí)驗(yàn)(可來電索取說明)

此產(chǎn)品本公司有標(biāo)記的一抗出售,相關(guān)標(biāo)記有:Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記


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