Anti-XBP-1抗體,細(xì)胞核轉(zhuǎn)錄因子X盒結(jié)合蛋白抗體

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Anti-XBP-1抗體,細(xì)胞核轉(zhuǎn)錄因子X盒結(jié)合蛋白抗體，規(guī)格0.1ml/0.2ml,提供，：.

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產(chǎn)品名稱：Anti-XBP-1抗體,細(xì)胞核轉(zhuǎn)錄因子X盒結(jié)合蛋白抗體

產(chǎn)品編號：BYK-1668R

產(chǎn)品規(guī)格：0.1ml/0.2ml

產(chǎn)品價格：請

此產(chǎn)品本公司有標(biāo)記的一抗出售，相關(guān)標(biāo)記有：Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記

產(chǎn)品別名：X box-binding protein-1; XBP-1; XBP1; XBP2; Tax responsive element binding protein 5; TREB5; X box binding protein 2; XBP 1; XBP2; XBP1_HUMAN.

Anti-XBP-1抗體,細(xì)胞核轉(zhuǎn)錄因子X盒結(jié)合蛋白抗體產(chǎn)品介紹：This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5.

抗體來源：本公司抗體有兔來源和鼠來源等

克隆類型：兔來源為多抗，鼠來源為單抗

產(chǎn)品類型：一抗

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