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博研生物強烈*“Anti-Exportin 1抗體,染色體區域穩定蛋白/核輸出蛋白1抗體-"，品質保障，*，提供，實驗無結果可免費退換！：
產品名稱：Anti-Exportin 1抗體,染色體區域穩定蛋白/核輸出蛋白1抗體-
產品編號：BYK-10151R
產品規格：0.1ml/0.2ml
英文名稱 Exportin 1
中文名稱 染色體區域穩定蛋白/核輸出蛋白1抗體
別 名 Chromosome region maintenance 1 protein homolog; CRM 1; CRM1; CRM1 homolog; DKFZp686B1823; Exp 1; Exp-1;Exp1; Exportin 1; Exportin1; Exportin-1; XPO 1; XPO1; XPO1_HUMAN.
研究領域 細胞生物 染色質和核信號 信號轉導 表觀遺傳學
抗體來源：本公司抗體有兔來源和鼠來源等
克隆類型：兔來源為多抗，鼠來源為單抗
產品類型：一抗
此抗體本公司有單抗和多抗，可用于免疫組化（IHC），免疫印跡（WB），酶聯免疫(ELISA)，IF、IP、流式細胞術等實驗（可來電索取說明）
此產品本公司有標記的一抗出售，相關標記有：Alexa Fluor 350 標記、Alexa Fluor 488 標記、Alexa Fluor 555 標記、Alexa Fluor 647 標記、AP標記、APC標記、Biotin標記、Cy3標記、Cy5標記、Cy5.5標記、Cy7標記、FITC標記、Gold標記、HRP標記、PE標記、PE-Cy3標記、PE-CY5標記、PE-CY5.5標記、PE-CY7標記、RBITC標記
Anti-Exportin 1抗體,染色體區域穩定蛋白/核輸出蛋白1抗體-產品介紹：The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jul 2008]
Function:
Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of an nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Involved in U3 snoRNA transport from Cajal bodies to nucleoli. Binds to late precursor U3 snoRNA bearing a TMG cap. Several viruses, among them HIV-1, HTLV-1 and influenza A use it to export their unspliced or incompley spliced RNAs out of the nucleus. Interacts with, and mediates the nuclear export of HIV-1 Rev and HTLV-1 Rex proteins. Involved in HTLV-1 Rex multimerization.
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Anti-Exportin 1抗體,染色體區域穩定蛋白/核輸出蛋白1抗體-優勢產品：
Anti-Apollon/FITC 熒光素標記Apollon凋亡抑制蛋白抗體IgG
Anti-APP/FITC 熒光素標記APP淀粉樣肽前體蛋白抗體IgG
Anti-APP695/770 /FITC 熒光素標記淀粉樣肽前體蛋白抗體IgG
Anti-APPL1/FITC 熒光素標記抗銜接因子蛋白含pH域磷酸*結合域和*拉鏈基元1抗體IgG
anti-AQP1/FITC 熒光素標記水通道蛋白-1抗體IgG
Anti-AQP-2/FITC 熒光素標記水通道蛋白-2蛋白抗體IgG
Anti-AQP-3/FITC 熒光素標記水通道蛋白-3抗體IgG
Anti-AQP4/FITC 熒光素標記水通道蛋白-4蛋白抗體IgG
Anti-AQP5/FITC 熒光素標記水通道蛋白-5抗體IgG
Anti-AQP7/FITC 熒光素標記水通道蛋白-7抗體IgG
Anti-AQP9/FITC 熒光素標記水通道蛋白-9抗體IgG
Anti-AR/FITC 熒光素標記雄激素受體抗體IgG
Anti-AKR1B1/ADR/FITC 熒光素標記醛糖還原酶抗體IgG
Anti-phospho-AR ( p-Ser580)/FITC 熒光素標記磷酸化雄激素受體抗體IgG
Anti-ARα1/FITC 熒光素標記α1腎上腺素能受體抗體IgG
Anti-ARC/FITC 熒光素標記ARC抗體IgG
Anti-ARF6/FITC 熒光素標記ADP核糖基化因子6抗體IgG
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