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小鼠抗血管內(nèi)皮生長因子A抗體

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產(chǎn)品簡介

小鼠抗血管內(nèi)皮生長因子A抗體產(chǎn)品介紹：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

詳細(xì)介紹

英文名稱	VEGF-A
中文名稱	小鼠抗血管內(nèi)皮生長因子A抗體
別名	Vascuoar endothelial growth factor A; vascular endothelial growth factor A isoform 2 precursor; Vegf; VEGF164; VEGFA; MGC70609; MVCD1; VEGF; VPF.
說明書	0.1ml 0.2ml
研究領(lǐng)域	腫瘤免疫學(xué) 生長因子和激素血管內(nèi)皮細(xì)胞
抗體來源	Mouse
克隆類型	Monoclonal
交叉反應(yīng)	Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, Guinea Pig,
產(chǎn)品應(yīng)用	WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	40-45kDa
性狀	Lyophilized or Liquid
濃度	1mg/1ml
免疫原	KLH conjugated synthetic peptide derived from human VEGF-A
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存條件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
產(chǎn)品介紹	background: This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.