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兔抗雞IgY抗體

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產品簡介

兔抗雞IgY抗體儲存液：0.01M PBS, pH 7.4。

詳細介紹

英文名稱	Chicken IgY
中文名稱	兔抗雞IgY抗體
別名	Egg yolk immunoglobulin; IgY.
說明書	0.1ml
研究領域	免疫學
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Chicken,
產品應用	WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	180kDa
性狀	Lyophilized or Liquid
濃度	1mg/1ml
免疫原	Chicken IgY
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M PBS, pH 7.4
保存條件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
產品介紹	background: In chickens, immunoglobulin Y is the functional equivalent to Immunoglobulin G (IgG). Like IgG, it is composed of two light and two heavy chains. Structurally, these two types of immunoglobulin differ primarily in the heavy chains, which in IgY have a molecular mass of about 65,100 atomic mass units (amu), and are thus larger than in IgG. The light chains in IgY, with a molar mass of about 18,700 amu, are somewhat smaller than the light chains in IgG. The molar mass of IgY thus amounts to about 167,000 amu. The steric flexibility of the IgY molecule is less than that of IgG.Functionally, IgY is partially comparable to Immunoglobulin E (IgE), as well as to IgG. However, in contrast to IgG, IgY does not bind to Protein A, to Protein G, or to cellular Fc receptors. Furthermore, IgY does not activate the complement system. The name Immunoglobulin Y was suggested in 1969 by G.A. Leslie and L.W. Clem, after they were able to show differences between the immunoglobulins found in chicken eggs, and immunoglobulin G. Other synonymous names are Chicken IgG, Egg Yolk IgG, and 7S-IgG. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 雞卵黃免疫球蛋白G抗體是一種7S免疫球蛋白，與哺乳動物IgG略有不同。該蛋白質分子量約為180kDa，含兩個亞單位，即67～70kDa的重鏈和22～30kDa的輕鏈，又稱IgY（Yolk immunoglobulin），存在于免疫后母雞的卵黃中。