巨噬細(xì)胞炎癥蛋白2（ GRＯβ）抗體相關(guān)標(biāo)記     Alexa Fluor 350   Alexa Fluor 488   Alexa Fluor 555   Alexa Fluor 647   AP  APC   Biotin   Cy3   Cy5  
 Cy5.5   Cy7   FITC   Gold   HRP   PE   PE-Cy3   PE-CY5   PE-CY5.5   PE-CY7  RBITC  
英文名稱     Anti-MIP2/GRO Beta/CXCL2
中文名稱     巨噬細(xì)胞炎癥蛋白2（ GRＯβ）抗體
別    名     C-X-C motif chemokine 2; Chemokine (C X C motif) ligand 2; Chemokine, CXC motif, ligand 2; CINC 2a; CINC2a; CINC3; CXC chemokine; CXCL 2; CXCL2; MIP2; MIP 2; MIP-2; Cytokine-induced neutrophil chemoattractant 3; GRO 2; GRO b; GRO protein, beta; Gro-beta; GRO2; GRO2 oncogene; GROb; GRObeta; Growth regulated protein beta; GROX; Macrophage inflammatory protein 2 alpha; Macrophage inflammatory protein 2; Melanoma growth stimulatory activity beta; MGSA b; MGSA beta; MGSAbeta; MIP 2; MIP 2a; MIP2 alpha; MIP2; MIP2A; MIP2alpha; SCYB 2; Scyb; SCYB2; Small inducible cytokine subfamily B, member 2.
抗體來源     Rabbit
克隆類型     polyclonal
交叉反應(yīng)     Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品類型     一抗  
 巨噬細(xì)胞炎癥蛋白2（ GRＯβ）抗體研究領(lǐng)域     免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子
蛋白分子量     predicted molecular weight: 12kDa
性    狀     Lyophilized or Liquid
免 疫 原     KLH conjugated synthetic peptide derived from human MIP2 C-terminus
亞    型     IgG
純化方法     affinity purified by Protein A
儲 存 液     0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品應(yīng)用      WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 
（石蠟切片需做抗原修復(fù)） 

 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.
保存條件     Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note     This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
 巨噬細(xì)胞炎癥蛋白2（ GRＯβ）抗體產(chǎn)品介紹    GRO beta is a member of the CXC, or chemokine class. It contains the ELR domain immediay preceding the first cysteine residue near the amino terminus. Other chemokines in this group include IL8, GRO alpha/beta/gamma, mouse KC, ENA78, GCP2, PBP/CTAPIII/beta TG/NAP2. These chemokines act primarily on neutrophils as chemoattractants and activators, including neutrophil degradation with release of myloperoxidase and other enzymes. GRO beta was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. GRO beta is an approximay 8 kDa polypeptide of 73 amino acids. The precursor form of GRO beta consists of 100 amino acids. To generate the mature GRO beta, the precursor cleaves its amino terminal 27 amino acids. GRO beta shows 60% amino acid homology to human GRO alpha and GRO gamma.
Function : Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
Subcellular Location : Secreted.
Post-translational modifications : The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
Similarity : Belongs to the intercrine alpha (chemokine CxC) family.
Database links : UniProtKB/Swiss-Prot: P19875.1