乙酰*羧化酶抗體（）

英文名稱：Anti-Acetyl CoA Carboxylase                         濃度： 1mg/1ml 

抗體來源：Rabbit

克隆類型：polyclonal          

 交叉反應：Human, Mouse, Rat, Cow, Monkey,

產品類型: 一抗  

性    狀:Lyophilized or Liquid 

保存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

產品介紹 ：Acetyl-CoA carboxylase （ACC） is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. 

Function : ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. 
Subunit : Monomer, homodimer, and homotetramer. Can form filamentous polymers. Interacts with MID1IP1; interaction with MID1IP1 promotes oligomerization and increases its activity.
Subcellular Location : Endomembrane system. Note=May associate with membranes.
Tissue Specificity : Predominantly expressed in the heart, skeletal muscles and liver.
Similarity : Contains 1 ATP-grasp domain.
Contains 1 biotin carboxylation domain. 
Contains 1 biotinyl-binding domain. 
Contains 1 carboxyltransferase domain.

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單克隆抗體定制服務，多克隆抗體定制，單克隆抗體純化   ，多克隆抗體純化  ，

抗體HRP標記  ，抗原HRP標記  ，抗體膠體金標記，抗體FITC標記，小鼠單抗Ig類/亞類鑒定，獸用細胞水平檢測（比如干擾素等），多肽半抗原的偶聯，

親和層析柱制備 （客戶提供抗原抗體）