髓系、淋巴、混合系白血病易位基因10抗體（）
英文名稱： Anti-AF10/MLLT10 濃度： 1mg/1ml
抗體來源：Rabbit
克隆類型：polyclonal
交叉反應：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
產品類型: 一抗
性 狀:Lyophilized or Liquid
保存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 ：A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t（10;11）（p12;q23） with MLL/HRX. The result is a rogue activator protein.
A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t（10;11）（p13;q14） with PICALM.
Function : Probably involved in transcriptional regulation. In vitro or as fusion protein with MLL has transactivation activity. Binds to cruciform DNA.
Subunit : Self-associates. Interacts with FSTL3 isoform 2; the interaction enhances MLLT10 in vitro transcriptional activity and self-association. Interacts with YEATS4. Interacts with SS18. Interacts with DOT1L.
Subcellular Location : Nucleus.
Tissue Specificity : Expressed abundantly in testis.
Post-translational modifications : Phosphorylated upon DNA damage, probably by ATM or ATR.
DISEASE : Note=A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t（10;11）（p12;q23） with MLL/HRX. The result is a rogue activator protein.
Note=A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t（10;11）（p13;q14） with PICALM.
Similarity : Contains 2 PHD-type zinc fingers.
Database links : UniProtKB/Swiss-Prot: P55197.1
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抗體HRP標記 ，抗原HRP標記 ，抗體膠體金標記，抗體FITC標記，小鼠單抗Ig類/亞類鑒定，獸用細胞水平檢測（比如干擾素等），多肽半抗原的偶聯，
親和層析柱制備 （客戶提供抗原抗體）
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