磷酸化腺苷單磷酸活化蛋白激酶α2抗體()
英文名稱: Anti-phospho-AMPK alpha 2 (Ser175) 濃度: 1mg/1ml
抗體來源:Rabbit
克隆類型:polyclonal
交叉反應:Human, Mouse, Rat,
產品類型: 一抗
性 狀: Lyophilized or Liquid
保存條件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 :Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
Similarity : Belongs to the protein kinase superfamily.
CAMK Ser/Thr protein kinase family.
SNF1 subfamily.
Contains 1 protein kinase domain.
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