產品名稱：Anti-MTMR14抗體,肌管素相關蛋白14抗體

產品編號：BYK-11217R

產品規格：0.1ml/0.2ml

產品價格：請

性 狀：Lyophilized or Liquid

濃 度：1mg/1ml

亞 型：IgG

貯 存：貯存于-20℃.

抗體來源：本公司抗體有兔來源和鼠來源等

克隆類型：兔來源為多抗，鼠來源為單抗

產品類型：一抗

此抗體本公司有單抗和多抗，可用于免疫組化（IHC），免疫印跡（WB），酶聯免疫(ELISA)，IF、IP、流式細胞術等實驗（可來電索取說明）

此產品本公司有標記的一抗出售，相關標記有：Alexa Fluor 350 標記、Alexa Fluor 488 標記、Alexa Fluor 555 標記、Alexa Fluor 647 標記、AP標記、APC標記、Biotin標記、Cy3標記、Cy5標記、Cy5.5標記、Cy7標記、FITC標記、Gold標記、HRP標記、PE標記、PE-Cy3標記、PE-CY5標記、PE-CY5.5標記、PE-CY7標記、RBITC標記

Anti-MTMR14抗體,肌管素相關蛋白14抗體產品背景介紹：Myotubularin-related protein 14 (MTMR14), also known as Jumpy, is a myotubularin-related phosphoinositol-3-phosphate (PI3P) phosphatase (1). Mutations in the MTMR14 gene have been associated with centronuclear myopathy (1). MTMR14 deficiency in mice leads to altered calcium homeostasis and muscle disorders (2). MTMR14 has also been shown to play a role in autophagy, a process that is highly regulated by phosphatidylinositides through the type III PI3K, Vps34 (3). MTMR14 was localized to autophagic isolation membranes and early autophagosomes (3). In these studies, MTMR14 inhibited autophagy and mutations of MTMR14 associated with centronuclear myopathy were also defective in autophagy inhibition. In zebrafish, MTMR14 knockdown was shown to increase the number of autophagosomes, suggesting that its activity is associated with an inhibition of autophagy (4).

保存條件:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃

重要提示: 本產品提供僅供研究使用，不用于人類治療或診斷.

優勢產品：

Anti-ASH1L抗體,KMT2H蛋白抗體
Anti-ABCA12抗體,腺苷三磷酸結合盒轉運體12抗體
Anti-ABCB9抗體,腺苷三磷酸結合盒轉運體9抗體
Anti-ABCD4抗體,三磷酸腺苷結合盒轉運蛋白4抗體
Anti-ABLIM3抗體,肌動蛋白結合蛋白LIM3抗體
Anti-ACBD3抗體*,高爾基復合體相關蛋白1抗體
Anti-ADAM12抗體,去整合素樣金屬蛋白酶12
Anti-AX2R抗體,膜粘連蛋白2受體抗體
Anti-AKAP7抗體,蛋白激酶A錨定蛋白7抗體
Anti-ADRA2C抗體,α2C-AR腎上腺素能受體抗體
Anti-AAV5 capsid protein VP1抗體,腺相關病毒5 VP1抗體
Anti-ACCN2抗體,腦鈉通道蛋白2抗體
Anti-APXL抗體,APXL蛋白抗體
Anti-ASIC3抗體,酸敏感離子通道蛋白3抗體
Anti-Aspartate beta hydroxylase抗體,天*β羥化酶抗體
Anti-AVPR2抗體,*加壓素受體2抗體
Anti-ARP3抗體,細胞骨架肌動蛋白樣蛋白3抗體
Anti-ANKRD5抗體,錨蛋白重復域5抗體
Anti-ANO9抗體,p53誘導蛋白5抗體