試劑：氨基喋呤 Aminopterin 氨基喋呤
Aminopterin 氨基喋呤 說明：生化研究或者抗*。 氨基喋呤 Aminopterin Descriptions Linkage More potent, but more toxic, than methotrexate. Biochem/physiol Actions Folic acid antagonist. Aminopterin is actively transported into cells by the folate transporter. In the cell, it is converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase that, in turn,binds to dihydrofolate reductase and inhibits its activity. Aminopterin-polyglutamate is degraded intracellularly by γ-glutamyl hydrolase. Properties Assay…………………….. ~98% （TLC） form ………………………...powder color………………………... yellow solubility ……………… 2 M NaOH: 50 mg/mL Solutions may be stored for 1-2 days at 4°C. DMSO: Solutions may be stored for 1-2 days at 4°C.soluble abs…………………………. ε1M/261 nm, 0.1 M NaOH 25,700 ε1M/282 nm, 0.1 M NaOH 24,500 ε1M/373 nm, 0.1 M NaOH 8,100 storage temp. −20°C TEST SPECIFICATION APPEARANCE YELLOW TO YELLOW WITH A BROWN CAST POWDER SOLUBILITY CLEAR YELLOW TO LIGHT BROWN SOLUTION AT 25MG PLUS 0.5ML OF 2M AMMONIUM HYDROXIDE WATER CONTENT NMT 9.3% （2.5MOL/MOL） NMR SPECTRUM CONSISTENT WITH STRUCTURE PURITY BY THIN LAYER CHROMATOGRAPHY APPROX. 98% RECOMMENDED RETEST 6 YEARS DOCUMENT # A1784/4/3/92/1 更多產品請登錄上海瓦蘭生物科技有限責任公司 *：http://www.wksubio.com 瓦蘭全國統一免費： ：
產品名稱 編號 規格 價格 Aminopterin 氨基喋呤 WK0092 5mg 420.00 Aminopterin 氨基喋呤 WK0092 10mg 800.00
別名：氨基蝶翅素；4-氨基*；4-Amino-PGA；4-Aminofolic acid；4-Aminopteroyl-L-glutamic acid
分子式：C 1 9H 2 0N 8O 5 分子量：440.41
CAS＃：54-62-6
外觀：黃色針狀結晶
特性：純度：98% （TLC）
溶解性：可溶于2 M NaOH，參考濃度 50 mg/mL4 ℃可
儲存1-2天。也可溶于DMSO，4℃可儲存1-2天。
R：61-28 S：53-28-36/37-45
儲存條件：-20℃
From Sigma A1784
