產品名稱：Sulfo-NHS
貨號：Pierce 24510
規(guī)格：500MG
Thermo Scientific Pierce Sulfo-NHS （N-hydroxysulfosuccinimide） and its uncharged analog NHS （N-hydroxysuccinimide） are chemical modification reagents for converting carboxyl groups to amine-reactive Sulfo-NHS esters for application in a variety of bioconjugation and crosslinking methods.
Derivatives are easily synthesized by mixing the Sulfo-NHS with a carboxyl-containing molecule and a dehydrating agent such as the carbodiimide EDC （EDAC）. The method is the basis for generating many types of protein labeling reagents, including amine-reactive fluorescent dyes, biotin affinity tags and pegylation compounds.
Highlights:
Efficiency of EDC-mediated coupling is increased in the presence of Sulfo-NHS
Amine-reactive Sulfo-NHS esters can be created on any carboxyl-containing molecule
Sulfo-NHS derivatives are water-soluble, so crosslinking can be done in physiologic solutions
High-purity, crystalline Sulfo-NHS can be used to create high-purity activated derivatives
Applications:
Improve efficiency of EDC coupling reactions
Convert carboxyls to amine-reactive Sulfo-NHS esters
Crosslink proteins to carboxyl-coated beads or surfaces more efficiently
Activate nanoparticles with amine-reactive Sulfo-NHS esters
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Sulfo-NHS原現貨 產品信息
