產品名稱：DSS, 50MG
貨號：Pierce 21655
規格：50MG
Thermo Scientific Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide （NHS） ester at each end of an 8-carbon spacer arm.
NHS esters react with primary amines at pH 7-9 to form stable amide bonds, along with release of the N-hydroxysuccinimide leaving group. Proteins, including antibodies, generally have several primary amines in the side chain of lysine （K） residues and the N-terminus of each polypeptide that are available as targets for NHS-ester crosslinking reagents.
DSS is first dissolved in an organic solvent such as DMF or DMSO, then added to the aqueous crosslinking reaction. BS3, the water soluble analog of DSS is also available for applications that require a hydrophilic crosslinker （e.g. to effect cell-surface crosslinking）. DSS and BS3 have essentially identical crosslinking activity toward primary amines.
DSS Highlights
Amine reactive Sulfo-NHS ester reacts rapidly with any primary amine-containing molecule
DSS crosslinker is membrane permeable, so intracellular crosslinking can be done
High purity, crystalline DSS can be used to create high-purity conjugates
Applications for DSS
Chemical crosslinking of intracellular proteins prior to cell lysis and immunoprecipitation
“Fix” protein interactions to allow identification of weak or transient protein interactions
Protein crosslinking to create bioconjugates via single-step reactions
Immobilize proteins onto amine-coated surfaces
上海葉舟生物科技有限公司(上海浩然生物技術有限公司)在為生命科學領域提供豐富的產品與信息資源方面處于全國*地位，公司提供的產品涵蓋了二十多個國家近五十萬種產品，而且產品的數量與信息在不斷的增長和更新，公司提供的產品能夠使生命科學工作者加快對生物化學，分子生物學，細胞生物學以及蛋白質組學研究的認知，以及分子診斷和臨床醫學領域的應用。
為方便客戶檢索資料，公司建立了數據強大的網站:
為方便客戶與公司交流，公司設立了在線服 QQ:470003480 496799915
為方便客戶訂購產品，公司設立了直線電話: 021- 51870956 54046790
生物試劑
DSS, 50MG 原裝現貨 產品信息
