5-氮雜-2-脫氧胞苷，SIGMA A3656-5mg

分類 其他生化試劑

級(jí)別 優(yōu)級(jí)純GR

含量 ≥97（％）

產(chǎn)品規(guī)格 SIGMA A3656-5MG

CAS  2353-33-5

品牌 Sigma

用途范圍 生物科研

保存溫度 常溫

分子式 C8H12N4O4

分子量 228.21

供應(yīng)商  上海研伴實(shí)業(yè)有限公司

5-氮雜-2-脫氧胞苷           SIGMA A3656-5MG

≥97%

· 產(chǎn)品編號(hào)：A3656

· 中文名稱：5 - 氮雜-2-脫氧胞苷

· 英文名稱：5-Aza-2-deoxycytidine

· CAS號(hào)：2353-33-5

· 分子式：C8H12N4O4

· 分子量：228.21

· 純度：≥97%

· 保存溫度：常溫

訂貨信息：

產(chǎn)品規(guī)格價(jià)格(RMB)

· A3656-5MG    電儀/元

· A3656-10MG    電儀/元

· A3656-50MG    電儀/元

注：此價(jià)格僅供參考，請(qǐng)以SIGMA價(jià)格為準(zhǔn)，優(yōu)惠價(jià)請(qǐng)電詢。

性能描述

General description

Decitabine is an epigenetic modifier that inhibits DNA methyltransferase activity which results in DNA demethylation (hypomethylation) and gene activation by remodeling opening chromatin. Genes are synergistically reactivated when demethylation is combined with histone hyperacetylation.

Biochem/physiol Actions

5′-Azadeoxycytidine causes DNA demethylation or hemi-demethylation. DNA demethylation can regulate gene expression by opening the chromatin structure detectable as increased nuclease sensitivity. This remodeling of chromatin structure allows transcription factors to bind to the promoter regions, assembly of the transcription complex, and gene expression.

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