人類表皮生長因子，SIGMA E9644-5×0.2MG

分類 抗體

含量 ≥97 (SDS-PAGE)（％）

產品規格 SIGMA E9644-5×0.2MG

CAS 62253-63-8

品牌 SIGMA

用途范圍 生物科研

保存溫度 -20℃

英文名稱 Epidermal Growth Factor human-EGF human

供應商      上海研伴實業有限公司

表皮生長因子 人類       SIGMA E9644-5X0.2MG

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

· 產品編號：E9644

· 中文名稱：表皮生長因子 人類

· 英文名稱：Epidermal Growth Factor human-EGF human

· 英文別名:EGF LONG® EGF

· CAS號：62253-63-8

· 純度：≥97% (SDS-PAGE)

· 保存溫度：−20 °C

· MDL號：MFCD00132565

訂貨信息：

產品規格價格(RMB)

· E9644-0.2MG2,999.88元

· E9644-5X0.2MG13,209.30元

注：此價格僅供參考，請以SIGMA價格為準，優惠價請電詢。

性能描述

Analysis Note

≥98% SDS-PAGE

Biochem/physiol Actions

Qualified for use as a mitogen for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline

Application

Qualified for use as a mitogen for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.

General description

Epidermal Growth Factor (EGF) is a small mitogenic polypeptide which is present in many mammalian species and is distributed throughout a wide number of tissues and body fluids. Human EGF is identical to β-urogastrone, a polypeptide which was recognized and isolated on the basis of its ability to inhibit gastric acid secretion. EGF is a member of a growth factor family which is characterized by the presence of 6 conserved cysteine motifs that form three disulfide bonds. The location of 3 intrachain disulfide bonds in recombinant human EGF is identical to that of mouse EGF. EGF is structurally homologous to human transforming growth factor-α (TGF-alpha), and both exert their actions through EGF receptors. EGF is homologous to a sequence contained in a 19 kD protein of vaccinia virus, which appears to utilize the EGF receptor to gain entry into cells.

EGF is mitogenic for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.

法律信息

LONG 注冊商標 Novozymes Gropep Limited

Other Notes

The biological activity of recombinant, human EGF is measured by its ability to stimulate the mouse fibroblast cell line, BALB/3T3. The EC50 is defined as the effective concentration of growth factor that elicits a 50% increase in cell growth in a cell based bioassay.

性質

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人類表皮生長因子，SIGMA E9644-5×0.2MG