中文名稱：ALKB蛋白抗體

英文名稱：Anti-ABH1

產品編號：BYK-12565R

別名：ABH; ABH1; alkB; AlkB, alkylation repair homolog 1 (E. coli); ALKB1_HUMAN; ALKBH; ALKBH1; Alkylated DNA repair protein alkB homolog 1; Alkylation repair homolog 1; Alkylation repair, alkB homolog; Alpha-ketoglutarate-dependent dioxygenase ABH1; DNA lyase ABH1; hABH.  

產品介紹：ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.

此產品本公司有標記的一抗出售，相關標記有：Alexa Fluor 350 標記、Alexa Fluor 488 標記、Alexa Fluor 555 標記、Alexa Fluor 647 標記、AP標記、APC標記、Biotin標記、Cy3標記、Cy5標記、Cy5.5標記、Cy7標記、FITC標記、Gold標記、HRP標記、PE標記、PE-Cy3標記、PE-CY5標記、PE-CY5.5標記、PE-CY7標記、RBITC標記

規格：0.1ml/0.2ml

濃度：1mg/1ml

抗體來源：本公司抗體有兔來源和鼠來源等

克隆類型：兔來源為多抗，鼠來源為單抗

產品類型：一抗

Anti-ABH1抗體,ALKB蛋白抗體保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

避免反復凍融，保質期一年。

Anti-ABH1抗體,ALKB蛋白抗體多色熒光搭配的原則

多色分析方案中熒光抗體的選擇和搭配，會受到很多因素的制約：

檢測通道不能沖突：每個檢測通道只能選擇1種熒光素，各通道之間的熒光素可以隨意搭配（如FL1選擇了FITC標記的抗體，就不能再選擇Alexa Fluor488標記的抗體；而同組實驗的其余抗體選擇PE或者APC標記，都是可以隨意組合的）；

熒光強弱：所選各種熒光素光譜的重疊應當盡量減少，否則將會導致較大的補償。zui常用的4色熒光搭配是：FITC、PE、PerCP/PerCP-Cy5.5、APC； 

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