產(chǎn)品編號 yb-13957R
英文名稱 Anti-CC19orf57抗體
中文名稱 細(xì)胞因子誘導(dǎo)蛋白29kDa抗體
別 名 Cytokine induced protein of 29 kDa; Cytokine-induced protein of 29 kDa; HCC 1; HCC1; HSPC316; Nuclear protein Hcc 1; Nuclear protein Hcc-1; Proliferation associated cytokine inducible protein CIP29; Proliferation-associated cytokine-inducible protein CIP29; SAP domain-containing ribonucleoprotein; SARNP; SARNP_HUMAN.
Anti-CC19orf57抗體
說 明 書 0.1ml 0.2ml
研究領(lǐng)域 腫瘤 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 細(xì)胞周期蛋白 轉(zhuǎn)錄調(diào)節(jié)因子
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse,
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
細(xì)胞定位 細(xì)胞核
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CIP29
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-CC19orf57抗體
PubMed PubMed
產(chǎn)品介紹 background:
CIP29 is a 210 amino acid nuclear protein whose expression is upregulated by erythropoietin. Induction of CIP2 expression is associated with cell cycle progression and apoptosis. This transcription factor binds both single stranded (ss) and double stranded (ds) DNA, though it has higher affinity for ssDNA. CIP29 is expressed at low levels in pancreas, spleen, testis, liver, kidney, heart and thymus, and is found to be expressed at higher levels in pancreatic adenocarcinoma and hepatocellular carcinoma. A translocation t(11;12)(q23;q13) in acute myelomonocytic leukemia results in the coding region of CIP29 gene fused to exon 9 of the MLL gene, which encodes for a protein with the N-terminal SAP domain and two C-terminal nuclear localization signals of CIP29 and N-termial AT hooks and central DNA methyltransferase homology region of MLL.
Anti-CC19orf57抗體
Function:
Binds both single-stranded and double-stranded DNA with higher affinity for the single-stranded form. Specifically binds to scaffold/matrix attachment region DNA. Also binds single-stranded RNA. Enhances RNA unwinding activity of DDX39A. May participate in important transcriptional or translational control of cell growth, metabolism and carcinogenesis.
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鈺博生物另建有七大技術(shù)服務(wù)平臺（ELISA定制服務(wù)，免疫學(xué)檢測服務(wù)、分子生物學(xué)技術(shù)服務(wù)、蛋白表達(dá)與純化技術(shù)服務(wù)、抗體制備技術(shù)服務(wù)、細(xì)胞培養(yǎng)技術(shù)服務(wù)、整體實(shí)驗(yàn)課題服務(wù)）并代理國外試劑：abcam 抗體；MBL，eBioscience，BD，R&D,Santan,CST,RayBiotech等品牌試劑，用專業(yè)的知識、專業(yè)的設(shè)備、專業(yè)的態(tài)度為客戶提供一站式實(shí)驗(yàn)技術(shù)服務(wù)！
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