產品編號 yb-8247R
英文名稱 Anti-COBL抗體
中文名稱 耳聾-甲狀腺腫綜合征相關COBL蛋白抗體
別 名 cobL; COBL_HUMAN; DKFZp686G13227; KIAA0633; MGC131893; Protein cordon-bleu.
Anti-COBL抗體
說 明 書 0.1ml 0.2ml
研究領域 心血管 細胞生物 免疫學 發育生物學 神經生物學
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Pig, Cow, Horse,
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 136kDa
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human COBL
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
產品介紹 background:
Cordon-bleu, also known as COBL, is a 1,261 amino acid protein that localizes to the node of the axial midline, a structure that organizes morphogenesis of the vertebrate embryo. Widely conserved and existing as five alternatively spliced isoforms, Cordon-bleu interacts with Vangl2 to mediate closure of the midbrain neural tube and is highly expressed in pancreas, ovary, brain, liver, lung and kidney. Cordon-bleu contains three WH2 domains and is encoded by a gene that maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.
Similarity:
Contains 3 WH2 domains.
Database links:
UniProtKB/Swiss-Prot: O75128.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
上海鈺博生物科技有限公司是2012年5月由“海歸”組成的創業團隊與兩個專業投資機構發起成立的,以開發生產科研試劑和特色檢驗產品為方向,經過兩年多的努力,已經建立了免疫學和分子生物學的五個技術平臺,開發了ELISA/ELISpot酶聯免疫試劑盒、重組蛋白、熒光標記抗體、四聚體(Tetramer)特異性T細胞檢測試劑盒、Aimplex流式高通量多因子檢測、microRNA 表達譜分析和功能研究等系列產品和服務,研究論文在Nature、Eur. J. Immunol、The Journal of Immunology和Arthritis & Rheumatism等學術期刊上發表,與國內外免疫學、干細胞、傳染病和腫瘤研究及臨床檢驗領域的科學家們建立了良好的合作關系,形成了一定的品牌影響力。
鈺博生物另建有七大技術服務平臺(ELISA定制服務,免疫學檢測服務、分子生物學技術服務、蛋白表達與純化技術服務、抗體制備技術服務、細胞培養技術服務、整體實驗課題服務)并代理國外試劑:abcam 抗體;MBL,eBioscience,BD,R&D,Santan,CST,RayBiotech等品牌試劑,用專業的知識、專業的設備、專業的態度為客戶提供一站式實驗技術服務!
我們的優勢:完善、穩定的實驗體系,優秀的科研隊伍,實驗設備、準確可靠的實驗結果。稟存用戶*的原則,竭誠為您服務。質量是所有產品和服務關鍵的組成部分,我們通過質量和實力贏得客戶的信賴。產品的質量是企業的生命。